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Antigenic Specificity | ADIPOR1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed: 25855295, PubMed: 12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human ADIPOR1. Subcellular Localization: Cell membrane; Multi-pass membrane protein. Localized to the cell membrane and intracellular organelles. Tissue Specificity: Widely expressed (PubMed: 16044242). Highly expressed in heart and skeletal muscle (PubMed: 12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed: 12802337). Weakly expressed in colon, thymus and small intestine |
Other Names | [Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I; ADIPOR1; PAQR1; TESBP1A; CGI-45], [ADIPOR1CGI-45] |
Gene, Accession # | [ADIPOR1], Gene ID: 51094, NCBI: NP_001277482.1, UniProt: Q96A54 |
Catalog # | MBS179757 |
Price | $160, $340, $340 |
Order / More Info | ADIPOR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |