ICAD Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ICAD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 100ug/100ul |
| Applications | Peptide ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isof |
| Immunogen | Immunogen: Synthetic peptide conjugated to Antibody |
| Other Names | [Homo sapiens DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, mRNA; DNA fragmentation factor subunit alpha; DNA fragmentation factor subunit alpha; DFF45; DNA fragmentation factor 45 kDa subunit; inhibitor of CAD; DNA fragmentation factor, 45kDa, alpha polypeptide; DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD], [DFFA; DFFA; DFF1; ICAD; DFF-45] |
| Gene, Accession # | [ICAD], Gene ID: 1676, NCBI: NP_004392.1 |
| Catalog # | MBS416656 |
| Price | $230 |
| Order / More Info | ICAD Antibody from MYBIOSOURCE INC. |
| Product Specific References | (1) Omata,K., Suzuki,R., Masaki,T., et al.Identification and characterization of the human inhibitor of caspase-activated DNase gene promoter. Apoptosis.13 (7), 929-937 (2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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