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Antigenic Specificity | DUX4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DUX4 antibody detects endogenous levels of total DUX4. Function: Involved in transcriptional regulation. May regulate microRNA (miRNA) expression.Subunit Structure: May exist as a monomer or a dimer.Similarity: Both homeobox domains confer nuclear targeting. Belongs to the paired homeobox family. |
Immunogen | Immunogen: A synthesized peptide derived from human DUX4 Subcellular Location: Nuclear Tissue Specificity: Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells. |
Other Names | [Double homeobox 4; Double homeobox protein 10; Double homeobox protein 4; Double homeobox protein 4/10; DUX10; DUX4L; DUX4L1] |
Gene, Accession # | [DUX4], Gene ID: 100288687, NCBI: NP_001280727.1, UniProt: Q9UBX2 |
Catalog # | MBS9608736 |
Price | $240, $280 |
Order / More Info | DUX4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |