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Antigenic Specificity | R Cask (Center), 589-616 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat (predicted reactivity: human, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.26 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Rat Cask antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of rat Cask. Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. |
Immunogen | n/a |
Other Names | [Peripheral plasma membrane protein CASK; Calcium/calmodulin-dependent serine protein kinase; Cask] |
Gene, Accession # | [Cask], Gene ID: 29647, NCBI: NP_071520.1, UniProt: Q62915 |
Catalog # | MBS9212475 |
Price | $165, $370 |
Order / More Info | R Cask (Center), 589-616 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hata Y., et al. J. Neurosci. 16:2488-2494(1996). Butz S., et al. Cell 94:773-782(1998). Hsueh Y.P., et al. Nature 404:298-302(2000). Tabuchi K., et al. J. Neurosci. 22:4264-4273(2002). Chetkovich D.M., et al. J. Neurosci. 22:6415-6425(2002). |