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Antigenic Specificity | PLEKHO1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. |
Immunogen | Immunogen: Recombinant Human Pleckstrin homology domain-containing family O member 1 protein (143-404AA) |
Other Names | [Pleckstrin homology domain-containing family O member 1PH domain-containing family O member 1; C-Jun-binding protein; JBP; Casein kinase 2-interacting protein 1; CK2-interacting protein 1; CKIP-1; Osteoclast maturat; PLEKHO1; CKIP1; OC120; HQ0024c] |
Gene, Accession # | [PLEKHO1], Gene ID: 51177, NCBI: NP_001291651.1, UniProt: Q53GL0 |
Catalog # | MBS7050401 |
Price | $160, $235 |
Order / More Info | PLEKHO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |