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Antigenic Specificity | ATAT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylatio |
Immunogen | Immunogen: Recombinant Human Alpha-tubulin N-acetyltransferase 1 protein (194-238AA) |
Other Names | [Alpha-tubulin N-acetyltransferase 1; Acetyltransferase mec-17 homolog; ATAT1] |
Gene, Accession # | [ATAT1], Gene ID: 79969, NCBI: NP_001026892.1, UniProt: Q5SQI0 |
Catalog # | MBS7107312 |
Price | $160, $235 |
Order / More Info | ATAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |