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Antigenic Specificity | KCNQ3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.7mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total KCNQ3 protein. This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. |
Immunogen | Immunogen: Synthetic peptide of human KCNQ3 Immunogen Type: Peptide |
Other Names | [EBN2; BFNC2; KV7.3] |
Gene, Accession # | [KCNQ3], Gene ID: 3786, NCBI: NP_001191753.1, UniProt: O43525 |
Catalog # | MBS9417183 |
Price | $255 |
Order / More Info | KCNQ3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |