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Antigenic Specificity | AIF (aa517-531) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human AIF antibody recognizes human Apoptosis-inducing factor 1, mitochondrial, also known as Programmed cell death protein 8 or apoptosis inducing factor (AIF). AIF is a 613 amino acid member of the FAD-dependent oxidoreductase family.Rabbit anti Human AIF antibody reacts with an internal region of AIF (within the region aa 517-531. AIF is widely expressed in human tissues and localizes in the mitochondria. AIF translocates to the nucleus upon induction of apoptosis. Multiple isoforms of AIF are generated by alternative splicing. Rabbit anti Human AIF antibody recognizes isoforms 1, 2,3 and 5. It is not expected to recognize either isoforms 4 or 6 as they lack the immunogen sequence. Mutations in the AIFM1 can result in various |
Immunogen | Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to AIF were raised by repeated immunisation of rabbit with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography. Target Species: Human |
Other Names | [apoptosis-inducing factor 1, mitochondrial isoform 4; Apoptosis-inducing factor 1, mitochondrial; apoptosis-inducing factor 1, mitochondrial; Neuropathy, axonal motor-sensory, with deafness and mental retardation; neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome); programmed cell death 8 (apoptosis-inducing factor); striatal apoptosis-inducing factor; apoptosis-inducing factor, mitochondrion-associated, 1; Programmed cell death protein 8], [AIFM1; AIFM1; AIF; CMT2D; CMTX4; COWCK; NADMR; NAMSD; PDCD8; COXPD6; AIF; PDCD8] |
Gene, Accession # | [AIF], Gene ID: 9131, NCBI: NP_001124318.1, UniProt: O95831 |
Catalog # | MBS221629 |
Price | $375 |
Order / More Info | AIF (aa517-531) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |