PABPN1 - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPABPN1 - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcript
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PABPN1
Other Names[polyadenylate-binding protein 2 isoform 1; Bcl-2-like protein 2; polyadenylate-binding protein 2; poly(A) binding protein nuclear 1; Apoptosis regulator Bcl-W]
Gene, Accession #[PABPN1], Gene ID: 8106, NCBI: NP_004634.1, UniProt: Q92843
Catalog #MBS3219795
Price$335
Order / More InfoPABPN1 - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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