MAP3K12 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP3K12
Clone[473CT23.12.5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatammonium sulfate precipitate
Size0.2 mL
Concentration2.12mg/ml
ApplicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionSpecificity: Human MAP3K12. This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq].
ImmunogenImmunogen: KLH-conjugated synthetic peptide mapping to a fragment of residue within amino acids 828-859 of human MAP3K12.
Other NamesMAP3K12 (MAP3K12, ZPK, Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, Leucine-zipper protein kinase, MAPK-upstream kinase, Mixed lineage kinase)
Gene, Accession #Gene ID: 7786, NCBI: AAH50050.1, UniProt: Q12852
Catalog #MBS645852
Price$610
Order / More InfoMAP3K12 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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