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Antigenic Specificity | Human MAPK8 / JNK1 / JNK |
Clone | [1A2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human MAPK8 / JNK1. JNK1, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK1 is phosphorylated by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK1 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four alternatively spliced transcript variants encoding distinct isoforms, 384 and 427 amino acids, have been identified. |
Immunogen | Immunogen Description: Recombinant protein |
Other Names | [MAPK8 / JNK1 / JNK (clone 1A2) IHC-plus; MAPK8; JNK; JNK1; JNK1A2; JNK-46; MAP kinase 8; PRKM8; SAPK1; SAPK1c; MAPK 8; C-Jun N-terminal kinase 1; JNK21B1/2; JUN N-terminal kinase; Human MAPK8; JNK1; JNK], [JNK1; JNK] |
Gene, Accession # | [MAPK8], Gene ID: 5599, NCBI: NP_620637.1, UniProt: P45983 |
Catalog # | MBS245550 |
Price | $605 |
Order / More Info | Human MAPK8 / JNK1 / JNK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |