Edit |   |
---|---|
Antigenic Specificity | MALT1 |
Clone | [50] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Functional Assay |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This recombinant mouse MIP-3a has been tested in bioassays for chemoattractant activity on CCR6-transfected 293 T cells with maximal activity observed between 10-100 ng/ml. The monoclonal antibody 50 recognizes human MALT1. MALT1 is a 91 kDa paracaspase that contains a death domain, two Ig-like domains and a C terminal caspase-like domain. Like other caspases, it cleaves substrates after an arginine residue. Expression is found in the cytoplasm of B and T cells. Within B cell follicles, MALT1 expression is highly expressed in centroblasts, followed by centrocytes and weakly expressed in the mantle zone. The interaction of MALT1 and Bcl10 occurs through Ig-like domains resulting in oligomerization and activation of the caspase-like domain. T |
Immunogen | n/a |
Other Names | [Mouse MALT1; MALT1; MALT1; MALT-1; MALT-1; MALT1; MALT-1; MALT 1; MALT 1; mucosa associated lymphoid tissue lymphoma translocation gene] |
Gene, Accession # | [MALT1], Gene ID: 10892, NCBI: BAA83099.1 |
Catalog # | MBS5309287 |
Price | $430 |
Order / More Info | MALT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |