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Antigenic Specificity | GRP78 BiP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, Immunocytochemistry ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for 78 kDa glucose-regulated protein(HSPA5) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat. Background: HSPA5(heat shock 70kDa protein 5) also known as glucose-regulated protein, 78kD(GRP78) or BiP, is a member of the heat-shock protein-70(HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum. BiP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. The HSPA5 gene is mapped on 9q33.3. Shen et al.(2002) concluded that HSPA5 retains ATF6 in the ER by inhibiting its Golgi localization signals |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human GRP78 BiP (603-617aa EWLESHQDADIEDFK), identical to the related mouse and rat sequences. |
Other Names | [78 kDa glucose-regulated protein; heat shock 70kDa protein 5(glucose-regulated protein, 78kDa); 78 kDa glucose regulated protein; 78 kDa glucose-regulated protein; AL022860; AU019543; BIP; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Endoplasmic reticulum lumenal Ca2+ binding protein grp78; FLJ26106; Glucose Regulated Protein 78kDa; GRP 78; GRP-78; GRP78; GRP78_HUMAN; Heat shock 70 kDa protein 5; Heat Shock 70kDa Protein 5; Hsce70; HSPA 5; HSPA5; Immunoglobulin Heavy Chain Binding Protein; Immunoglobulin heavy chain-binding protein; mBiP; MIF2; Sez7], [HSPA5; HSPA5; BIP; MIF2; GRP78; HEL-S-89n; GRP78; GRP-78; BiP] |
Gene, Accession # | [HSPA5], Gene ID: 3309, NCBI: P11021.2, UniProt: P11021 |
Catalog # | MBS176253 |
Price | $315 |
Order / More Info | GRP78 BiP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |