Mannose receptor, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mannose receptor, Human |
| Clone | 15-2 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 0.05 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), FS, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 15-2 recognizes the mannose receptor (MR), also known as CD206, a member of the vertebrate C-type lectin family. The mannose receptor, is a pattern recognition receptor that is involved in both innate and adaptive immunity. The 175 kDa single-pass type I transmembrane receptor consists of 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. The structure is shared by the family of multi lectin mannose receptors: the phospholipase A2-receptor, DEC 205 and the novel C-type lectin |
| Immunogen | Immunogen: Purified human mannose receptor from human placental tissue |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS584111 |
| Price | $465 |
| Order / More Info | Mannose receptor, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Barret-Berghoeff, M et al; Monoclonal antibodies against the human mannose receptor that inhibit the binding of tissue-type plasminogen activator. Thromb Haemostas 1997, 77: 718 2. Noorman, F et al; Monoclonal antibodies against the human mannose receptor as a specific marker in flow cytometry and immunohistochemistry for macrophages. J Leukocyte Biol 1997, 61: 63 3. Noorman, F et al; Cluster Mannosides can inhibit mannose receptor-mediated tissue-type plasminogen activator degradation by both rat and human cells. Hepatology 1997, 26: 1303 |
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MYBIOSOURCE INC.
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