Phospho-Smad Antibody Sampler Kit Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Smad Antibody Sampler Kit
Clonen/a
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size1 kit
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionBackground: Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-beta signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the receptor-regulated Smads (R-Smads), which include Smad1, 2, 3, 5, and 8; the common-mediator Smad (co-Smad), Smad4; and the antagonistic or inhibitory Smads (I-Smads), Smad6 and 7. Activated type I receptors associate with specific R-Smads and phosphorylate them on a conserved carboxy terminal SSXS motif. The phosphorylated R-Smad dissociates from the receptor and forms a heteromeric complex with the co-Smad (Smad4), allowing translocation of the complex to the nucleus. Once in the nucleus, Smads
Immunogenn/a
Other Namesn/a
Gene, Accession #[Smad]
Catalog #MBS2550154
Price$545
Order / More InfoPhospho-Smad Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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