DOK5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DOK5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: DOK5 antibody detects endogenous levels of total DOK5. Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.Subunit Structure: Interacts with phosphorylated RET. In contrast to other DOK proteins, it does not interact with RASGAP (By similarity).Post-translational Modifications: Phosphorylated on tyrosine residues in response to insulin, IGF1 and GDNF.Similarity: PTB domain mediates receptor interaction. Belongs to |
| Immunogen | Immunogen: A synthesized peptide derived from human DOK5 Tissue Specificity: Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (86%), Bovine (82%), Horse (100%), Rabbit (91%), Dog (100%), Chicken (82%), Xenopus (82%) |
| Other Names | [chromosome 20 open reading frame 180; Docking protein 5; DOK 5; DOK5; DOK5 protein; DOK5_HUMAN; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; IRS6] |
| Gene, Accession # | [DOK5], Gene ID: 55816, NCBI: NP_060901.2, UniProt: Q9P104 |
| Catalog # | MBS9608968 |
| Price | $240, $280 |
| Order / More Info | DOK5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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