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Antigenic Specificity | FAP/Fibroblast Activation Protein Alpha Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Fibroblast activation protein alpha is a 170 kDa melanoma membrane-bound gelatinase, protein that in humans is encoded by the FAP gene. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Protein Function: Cell |
Immunogen | Immunogen: E Coli-derived human FAP recombinant protein (Position: R550-A619). Subcellular Localization: Prolyl endopeptidase FAP: Cell surface. Tissue Specificity: Expressed in adipose tissue. Expressed in the dermal fibroblasts in the fetal skin. Expressed in the granulation tissue of healing wounds and on reactive stromal fibroblast in epithelial cancers. Expressed in activated fibroblast-like synoviocytes from inflamed synovial tissues. Expressed in activated hepatic stellate cells (HSC) and |
Other Names | [Prolyl endopeptidase FAP] |
Gene, Accession # | [FAP], Gene ID: 2191, NCBI: NP_001278736.1, UniProt: Q12884 |
Catalog # | MBS1750397 |
Price | $280 |
Order / More Info | FAP/Fibroblast Activation Protein Alpha Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |