Human VEGFR-1/Flt-1, Agonistic Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman VEGFR-1/Flt-1, Agonistic
Clone[8F12]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.2 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Stimulation
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DescriptionThis antibody recognizes hVEGFR-1 in Western blot. It shows no cross-reactivity with hVEGFR-2. Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but
Immunogenn/a
Other Names[Agonistic of Human VEGFR-1 (#8F12)], [FLT1; FLT1; FLT; FLT-1; VEGFR1; VEGFR-1; FLT; FRT; VEGFR1; VEGFR-1; FLT-1; FLT]
Gene, Accession #[VEGFR-1/Flt-1], Gene ID: 2321, NCBI: NP_001153392.1, UniProt: P17948
Catalog #MBS690544
Price$895
Order / More InfoHuman VEGFR-1/Flt-1, Agonistic Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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