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Antigenic Specificity | Human VEGFR-1/Flt-1, Agonistic |
Clone | [8F12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), Stimulation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes hVEGFR-1 in Western blot. It shows no cross-reactivity with hVEGFR-2. Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but |
Immunogen | n/a |
Other Names | [Agonistic of Human VEGFR-1 (#8F12)], [FLT1; FLT1; FLT; FLT-1; VEGFR1; VEGFR-1; FLT; FRT; VEGFR1; VEGFR-1; FLT-1; FLT] |
Gene, Accession # | [VEGFR-1/Flt-1], Gene ID: 2321, NCBI: NP_001153392.1, UniProt: P17948 |
Catalog # | MBS690544 |
Price | $895 |
Order / More Info | Human VEGFR-1/Flt-1, Agonistic Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |