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Antigenic Specificity | Caspase-9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, hamster, bovine, rabbit, porcine |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects proform (~46kDa), intermediate (~33-36 kDa), and the fully cleaved (~20-25kDa) caspase-9. Background: Caspase-9 is one of the most important caspases among the caspase family members. Caspase-9 is synthesized as inactive pro-enzyme that is processed in cells undergoing apoptosis. The processed caspase-9 consists of large (32-35 kD) and small (10 kD) subunits which associate to form an active enzyme. Activated caspase-9 in turn cleaves and activates caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 290 of human caspase-9 |
Other Names | [CASP-9; EC 3.4.22.62; ICE-like apoptotic protease 6,ICE-LAP6,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3; Apaf-3], [CASP9; CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; MCH6; CASP-9; APAF-3; ICE-LAP6] |
Gene, Accession # | Gene ID: 842, NCBI: BAA87905.1 |
Catalog # | MBS841177 |
Price | $305 |
Order / More Info | Caspase-9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |