C14orf169 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityC14orf169
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration0.8mg/mL
ApplicationsImmunohistochemistry (IHC), ELISA (EIA)
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DescriptionOxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or r
ImmunogenImmunogen: Synthetic peptide of human C14orf169
Other Names[60S ribosomal protein L8 histidine hydroxylase; C14orf169; Chromosome 14 open reading frame 169; Histone lysine demethylase NO66; HsNO66; Hypothetical protein FLJ21802; Lysine-specific demethylase NO66; MAPJD; MYC associated protein with JmjC domain; NO66; NO66; Nucleolar protein 66; Ribosomal oxygenase NO66; ROX; Up regulated in lung cancer 2; URLC2]
Gene, Accession #[C14orf169], Gene ID: 79697, NCBI: NP_078920, UniProt: Q9H6W3
Catalog #MBS2559632
Price$110, $150, $225
Order / More InfoC14orf169 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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