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Antigenic Specificity | KDM5B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2.7mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PLU-1 is a large (1, 544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin. |
Immunogen | Immunogen: Synthetic peptide of human KDM5B Calculated Molecular Weight: 176kDa |
Other Names | [CT31; PLU1; PUT1; PLU-1; JARID1B; RBBP2H1A] |
Gene, Accession # | [KDM5B] |
Catalog # | MBS2524317 |
Price | $110, $150, $225 |
Order / More Info | KDM5B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |