Human CEACAM1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CEACAM1
Clone[GM-8G5]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), CELISA and Immunohistology on cryosections
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DescriptionSpecificity: anti-human CEACAM1 (biliary glycoprotein I, BGP/CD66a). Background: CEACAM1 (BGP/CD66a) is a transmembrane glycoprotein which belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It is expressed on cells of epithelial and myeloid origin and mediates homophilic intercellular interactions that influence cellular growth, immune cell activation, and tissue morphogenesis. CEACAM1 is a putative tumour suppressor based on diminished expression in some aggressive types of cancer cells (3). The anti-tumour effect may be due to inhibition of tumour angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells (4). Like all members of the CEACAM family, it consists of a single N domain, with structu
ImmunogenImmunogen: Immunogen: cDNA
Other Names[CD66a; BGP; biliary glycoprotein I], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1]
Gene, Accession #Gene ID: 634, NCBI: NP_001020083.1, UniProt: P13688
Catalog #MBS468039
Price$505
Order / More InfoHuman CEACAM1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine(T. Creighton, ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggestedfunctions and expression in normal and malignant tissues. Semin. Cancer Biol. 9, 67-81.Luo W, Tapolsky M, Early K, Wood CG, Wilson DR, Logothetis CJ, Lin SH (1999). Tumorsuppressiveactivity of CD66a in prostate cancer. Cancer Gene Ther. 6(4): 313-21.Tilki D, Irmak S, Oliveira-Ferrer L, Hauschild J, Miethe K, Atakaya H, Hammerer P, FriedrichMG, Schuch G, Galalae R, Stief CG, Kilic E, Huland H, Ergun S (2006). CEA-related celladhesion molecule-1 is involved in angiogenic switch in prostate cancer. Oncogene 25(36):4965-74
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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