Human CD7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD7 |
| Clone | [4AeBio124-1D1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 50 tests, 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The 4AeBio124-1D1 monoclonal antibody reacts with human CD7, also known as gp40 and Leu9. CD7, a 40 kD receptor, is a member of the immunoglobulin gene superfamily. The N-terminal amino acid sequence (aa1-107) is highly homologous to Ig kappa light chain sequence; while the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T lymphocytes, and T cell leukemias. It is also found on natural killer cells, a small suppopulation of normal B cells and on maligant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity, as measured by calcium flux, expression of adhesion mol |
| Immunogen | n/a |
| Other Names | [CD7 antigen protein; T-cell antigen CD7; T-cell antigen CD7; CD7 molecule; GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41; CD_antigen: CD7] |
| Gene, Accession # | [CD7], Gene ID: 924, NCBI: AAA51953.1 |
| Catalog # | MBS8510510 |
| Price | $215, $280 |
| Order / More Info | Human CD7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Lyman SD, Escobar S, Rousseau AM, Armstrong A, Fanslow WC. Identification of CD7 as a cognate of the human K12 (SECTM1) protein. J Biol Chem. 2000 Feb 4; 275(5):3431-7. 2.Sato AI, Balamuth FB, Ugen KE, Williams WV, Weiner DB. Identification of CD7 glycoprotein as an accessory molecule in HIV-1-mediated syncytium formation and cellfree infection. J Immunol. 1994 May 15; 152(10):5142-52. (124-1D1, FA, FC, PubMed). 3.Aruffo A, Seed B. Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system.EMBO J. 1987 Nov; 6(11):3313-6. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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