UCHL3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | UCHL3 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3, and exhibits a preference towards 'Lys-48'-linked Ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin- signaling and insulin-induced adipogenesis. Required for stress- response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a |
| Immunogen | Immunogen: A synthesized peptide derived from human UCHL3 Subcellular Localization: Cytoplasm. Tissue Specificity: Highly expressed in heart, skeletal muscle, and testis. |
| Other Names | [Ubiquitin carboxyl-terminal hydrolase isozyme L3; UCH-L3; 3.4.19.12; Ubiquitin thioesterase L3; UCHL3] |
| Gene, Accession # | [UCHL3], Gene ID: 7347, NCBI: NP_001257881.1, UniProt: P15374 |
| Catalog # | MBS1750033 |
| Price | $160, $340, $340 |
| Order / More Info | UCHL3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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