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Antigenic Specificity | Caspase-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caspase-1 Polyclonal Antibody detects endogenous levels of Caspase-1 protein. CASP1 encodes a protein (caspase 1) which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis an |
Immunogen | Immunogen: Synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376 |
Other Names | [Rabbit Caspase-1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45] |
Gene, Accession # | [CASP1], Gene ID: 834, NCBI: NP_001214.1, UniProt: P29466 |
Catalog # | MBS9701579 |
Price | $130, $220, $325 |
Order / More Info | Caspase-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |