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Antigenic Specificity | CDC42 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of CDC42 protein. The protein encoded by CDC42 (Cell Division Cycle 42) is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of CDC42 results in mul |
Immunogen | Immunogen: Synthesized peptide derived from part region of human CDC42 protein at amino acid sequence of 80-160 |
Other Names | [Rabbit CDC42; Cell division control protein 42 homolog; G25K GTP-binding protein] |
Gene, Accession # | [CDC42], Gene ID: 998, NCBI: NP_001782.1, UniProt: P60953 |
Catalog # | MBS9708663 |
Price | $130, $220, $325 |
Order / More Info | CDC42 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |