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Antigenic Specificity | TNIP1 (C-term), 607-636 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.3 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TNIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 607-636 amino acids from the C-terminal region of human TNIP1. Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal (By similarity). Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. |
Immunogen | n/a |
Other Names | [TNFAIP3-interacting protein 1; A20-binding inhibitor of NF-kappa-B activation 1; ABIN-1; HIV-1 Nef-interacting protein; Nef-associated factor 1; Naf1; Nip40-1; Virion-associated nuclear shuttling protein; VAN; hVAN; TNIP1; KIAA0113; NAF1] |
Gene, Accession # | [TNIP1], Gene ID: 10318, NCBI: NP_001239315.1, UniProt: Q15025 |
Catalog # | MBS9205175 |
Price | $165, $370 |
Order / More Info | TNIP1 (C-term), 607-636 Antibody from MYBIOSOURCE INC. |
Product Specific References | He, C.F., et al. Lupus 19(10):1181-1186(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Gateva, V., et al. Nat. Genet. 41(11):1228-1233(2009) Han, J.W., et al. Nat. Genet. 41(11):1234-1237(2009) |