Tau (Tau46) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Tau (Tau46) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Tau (Tau46) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Tau is a heterogeneous microtubule-associated protein that promotes and stabilizes microtubule assembly, especially in axons. Six isoforms with different amino-terminal inserts and different numbers of tandem repeats near the carboxy-terminus have been identified, and tau is hyperphosphorylated at approximately 25 sites by ERK, GSK-3 and CDK5. Phosphorylation decreases the ability of tau to bind to microtubules. Neurofibrillary tangles are a major hallmark of Alzheimer's disease and these tangles are bundles of paired helical filaments composed of hyperphosphorylated tau. In particular, phosphorylation of Ser396 by GSK-3 or CDK5 destabilizes microtubules in Alzheimer's disease. Furthermore, inclusions of tau are found in a number of other n |
| Immunogen | Immunogen: Native bovine tau and the epitope maps to the carboxy-terminus of the protein. |
| Other Names | n/a |
| Gene, Accession # | [Tau] |
| Catalog # | MBS555595 |
| Price | $450 |
| Order / More Info | Tau (Tau46) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies