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Antigenic Specificity | Phospho-CX43(Tyr265) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-CX43(Tyr265)antibody detects endogenous levels of CX43. Function: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the re |
Immunogen | Immunogen: A synthesized peptide derived from human CX43 around the phosphorylation site of Tyr265. Subcellular Location: Cell Membrane. Cell Junction > Gap Junction. Tissue Specificity: Expressed in the heart and fetal cochlea. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (83%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (83%), Chicken (83%), Xenopus (100%) |
Other Names | [Connexin 43; Connexin-43; Cx 43; Cx43; CXA1_HUMAN; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; Gap junction protein alpha 1 43kDa (connexin 43); Gap junction protein alpha 1 43kDa; Gap junction protein alpha like; GJA 1; Gja1; GJAL; ODD; ODDD; ODOD; SDTY3] |
Gene, Accession # | [CX43], Gene ID: 2697, NCBI: NP_000156.1, UniProt: P17302 |
Catalog # | MBS9600634 |
Price | $240, $280 |
Order / More Info | Phospho-CX43(Tyr265) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |