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Antigenic Specificity | MASP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MASP2 antibody detects endogenous levels of total MASP2. Function: Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.Subunit Structure: Homodimer; disulfide-linked. Binds MBL2. Isoform 2 binds to MASP1. Binds SERPING1. Dimerization and MBL2 binding requires calcium ions.Post-translational Modifications: The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. Activated by cleavage after Arg-444. The uncleaved zymogen is inactive towards synthetic substrates, bu |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Extracellular Region or Secreted Tissue Specificity: Plasma. |
Other Names | [Mannan binding lectin serine peptidase 2; Mannan binding lectin serine protease 2; Mannose binding protein associated serine protease 2; MAP 19; MAP19; MASP 2; MBL associated plasma protein of 19 kD; MBL associated serine protease 2; Small MBL associated protein; sMAP] |
Gene, Accession # | [MASP2], Gene ID: 10747, NCBI: NP_006601.2, UniProt: O00187 |
Catalog # | MBS9605606 |
Price | $240, $280 |
Order / More Info | MASP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |