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Antigenic Specificity | PIM-1 (Phospho Tyr309) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Pim-1 (Y309) Polyclonal Antibody detects endogenous levels of Pim-1 protein only when phosphorylated at Y309. The protein encoded by PIM1 (Pim-1 proto-oncogene, serine/threonine kinase) belongs to the Ser/Thr protein kinase family, and PIM subfamily. PIM1 is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-fr |
Immunogen | Immunogen: Synthesized peptide derived from human Pim-1 around the phosphorylation site of Y309 |
Other Names | [Rabbit Pim-1 (phospho Tyr309); PIM1; Serine/threonine-protein kinase pim-1] |
Gene, Accession # | [PIM-1], Gene ID: 5292, NCBI: NP_001230115.1, UniProt: P11309 |
Catalog # | MBS9706220 |
Price | $130, $220, $325 |
Order / More Info | PIM-1 (Phospho Tyr309) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |