LDLRAP1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLDLRAP1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against LDLRAP1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. LDLRAP1 may also be involved in the internalization of other LD
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDLRAP1
Other Names[low density lipoprotein receptor adapter protein 1; Low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adaptor protein 1; Autosomal recessive hypercholesterolemia protein]
Gene, Accession #[LDLRAP1], Gene ID: 26119, NCBI: NP_056442, UniProt: Q5SW96
Catalog #MBS3212149
Price$335
Order / More InfoLDLRAP1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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