Edit |   |
---|---|
Antigenic Specificity | LDLRAP1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against LDLRAP1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. LDLRAP1 may also be involved in the internalization of other LD |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDLRAP1 |
Other Names | [low density lipoprotein receptor adapter protein 1; Low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adapter protein 1; low density lipoprotein receptor adaptor protein 1; Autosomal recessive hypercholesterolemia protein] |
Gene, Accession # | [LDLRAP1], Gene ID: 26119, NCBI: NP_056442, UniProt: Q5SW96 |
Catalog # | MBS3212149 |
Price | $335 |
Order / More Info | LDLRAP1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |