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Antigenic Specificity | IRS4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Insulin receptor substrate (IRS) proteins play a central role in maintaining basic cellular functions such as growth and metabolism through insulin/insulin like growth factor (IGF) signaling. Four members (IRS-1, IRS-2, IRS-3, IRS-4) of this family have been identified which differ in their subcellular distribution and interaction with SH2 domain proteins. After phosphorylation by activated receptors, these intracellular signaling molecules recruit various downstream effector pathways including phosphatidylinositol 3-kinase, tyrosine protein phosphatase SHPTP-2, and several smaller adapter molecules such as the growth factor receptor-binding protein Grb-2. |
Immunogen | Immunogen: IRS4 antibody was raised in Rabbit using a synthetic target peptide as the immunogen |
Other Names | [Rabbit IRS4; IRS4; IRS4; IRS4; insulin receptor substrate 4; 160 kDa phosphotyrosine protein; BOS_25677; insulin receptor substrate 2-A; insulin receptor substrate protein; insulin receptor substrate-undetermined designation; insulin receptor substrate-unique; IRS1; irs2; irs2-a; IRS-2-A; IRS-4; phosphoprotein of 160 kDa; pp160; py160; RP23-415G1.3; xIRS-u] |
Gene, Accession # | [IRS4], Gene ID: 8471, NCBI: NP_003595.1, UniProt: O14654 |
Catalog # | MBS5310061 |
Price | $375 |
Order / More Info | IRS4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |