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Antigenic Specificity | MCM4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head n |
Immunogen | Immunogen: A synthetic peptide of human MCM4 Observed Molecular Weight: 97kDa |
Other Names | [CDC21; CDC54; hCdc21; P1-CDC21] |
Gene, Accession # | [MCM4], Gene ID: 4173, NCBI: AAC52018.1 |
Catalog # | MBS2525789 |
Price | $150, $225, $360 |
Order / More Info | MCM4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |