Human CD11b/C3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD11b/C3
Clone[Bear-1]
Host SpeciesMouse (Balb/c)
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC), Immunoprecipitation (IP)
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DescriptionSpecificity: Bear-1 reacts with the CD11b alpha chain of the CD11b/CD18. Bear-1 precipitated a 165-95-kDa complex and is found to be similar to Mo-1 (monocyte differentiation antigen). Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (alphaMbeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B). The second chain of alphaMbeta2 is the common integrin beta2 subunit known as CD18, and integrin alphaMbeta2 thus belongs to the beta2 subfamily (or leukocyte) integrins. alphaMbeta2 is expressed on the surface of many leukocytes involved in the innate immune system, including monoc
ImmunogenSource Note: Bear-1 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with with purified Human monocytes.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS570201
Price$415
Order / More InfoHuman CD11b/C3 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesG.D. Keizer, J. Borst, C.G. Figdor, H. Spits, F. Miedema, C. Terhorst and J.E. de Vries.Biochemical and functional characteristics of the Human leukocyte membrane antigen family LFA-1, Mo-1 and p150,95. Eur. J. Immunol. 15: 1142-1147, 1985.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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