CD86 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD86 |
| Clone | [BU63] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat. |
| Isotype | IgG1, kappa |
| Format | phycoerythrin (PE) conjugate |
| Size | 0.5 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immuofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9). CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the majo |
| Immunogen | Immunogen: ARH-77 (B-lymphoblastoid cell line) Quantity and Buffer: 0.5 ml at 200ug/ml; Conjugated to PE |
| Other Names | [Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell costimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2], [CD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2] |
| Gene, Accession # | [CD86], Gene ID: 942, NCBI: NP_001193853.1, UniProt: P42081 |
| Catalog # | MBS438023 |
| Price | $340 |
| Order / More Info | CD86 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Engel P, Gribben JG, Freeman GJ, Zhou LJ, Nozawa Y, Abe M, Nadler LM, Wakasa H, Tedder TF: The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen. Blood. 1994;84(5):1402-7.2. Caux C, Vanbervliet B, Massacrier C, Azuma M, Okumura K, Lanier LL, Banchereau J: B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J Exp Med. 1994;180(5):1841-7.3. Mauri D, Wyss-Coray T, Gallati H, Pichler WJ: Antigen-presenting T cells induce the development of cytotoxic CD4 T cells. I. Involvement of the CD80-CD28 adhesion molecules. J Immunol. 1995;155(1):118-27.4. Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995).5. Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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