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Antigenic Specificity | OPTN - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against OPTN. It was validated on Western Blot using a cell lysate as a positive control.Target Description: OPTN is the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. This gene encodes the coiled-coil containi |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human OPTN |
Other Names | [optineurin; Optineurin; optineurin; optineurin; E3-14.7K-interacting protein; FIP-2; Huntingtin yeast partner L; Huntingtin-interacting protein 7; HIP-7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; TFIIIA-IntP] |
Gene, Accession # | [OPTN], Gene ID: 10133, NCBI: NP_068815, UniProt: Q96CV9 |
Catalog # | MBS3206953 |
Price | $365 |
Order / More Info | OPTN - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |