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Antigenic Specificity | Human L1CAM |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and in a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan and intergrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling. Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuff |
Immunogen | Immunogen: Recombinant Human CD171/N-CAML1/L1CAM protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [L1CAM, partial] |
Gene, Accession # | [L1CAM ] |
Catalog # | MBS2543857 |
Price | $295, $475, $735 |
Order / More Info | Human L1CAM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |