BMI1 (C-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBMI1 (C-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThis BMI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 281-314 amino acids from the C-terminal region of human BMI1. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Immunogenn/a
Other Names[Purified Rabbit (Pab); Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4; RNF51]
Gene, Accession #[BMI1], Gene ID: 100532731, NCBI: NP_001190991.1, UniProt: P35226
Catalog #MBS9216744
Price$165, $370
Order / More InfoBMI1 (C-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAlkema M.J.,et al.Hum. Mol. Genet. 2:1597-1603(1993). Ota T.,et al.Nat. Genet. 36:40-45(2004). Deloukas P.,et al.Nature 429:375-381(2004). Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Levy L.S.,et al.Oncogene 8:1833-1838(1993).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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