TP53 (N-term) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TP53 (N-term) antibody, protein, ELISA kits.
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| Antigenic Specificity | TP53 (N-term) |
| Clone | [1227CT355.106.153] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,kappa |
| Format | unconjugated |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.46 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Purified His-tagged TP53 protein was used to produced this monoclonal antibody. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cel |
| Immunogen | n/a |
| Other Names | [Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53; P53] |
| Gene, Accession # | [TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637 |
| Catalog # | MBS9200216 |
| Price | $165, $370 |
| Order / More Info | TP53 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lamb P., et al. Mol. Cell. Biol. 6:1379-1385(1986). Filippini G., et al. Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases. Zakut-Houri R., et al. EMBO J. 4:1251-1255(1985). Harlow E., et al. Mol. Cell. Biol. 5:1601-1610(1985). Harris N., et al. Mol. Cell. Biol. 6:4650-4656(1986). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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