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Antigenic Specificity | DAPK3 (Ab-265) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total DAPK3 protein. Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation, actin cytoskeleton reorganization, cell motility, smooth muscle contraction, and mitosis, particularly cytokinesis. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin p |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized non-phosphopeptide derived from human DAPK3 around the phosphorylation site of threonine 265 (R-M-T(p)-I-A). |
Other Names | [DAP kinase 3; DAP-like kinase; Death-associated protein kinase 3; Dlk; EC 2.7.11.1] |
Gene, Accession # | [DAPK3], Gene ID: 1613, NCBI: NP_001339.1, UniProt: O43293 |
Catalog # | MBS9415008 |
Price | $200, $255 |
Order / More Info | DAPK3 (Ab-265) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |