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Antigenic Specificity | BATF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total BATF protein. AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8+ dendritic cells and class-switch recombination (CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3'. The BATF-JUNB heterodimer also forms a complex with IRF4 (or IRF8) in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 (or IRF8) and activation of genes. Controls differentiatio |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human BATF. |
Other Names | [B-ATF; SF-HT-activated gene 2 protein; SFA-2] |
Gene, Accession # | [BATF], Gene ID: 10538, NCBI: NP_006390.1, UniProt: Q16520 |
Catalog # | MBS9405001 |
Price | $200, $255 |
Order / More Info | BATF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |