Edit |   |
---|---|
Antigenic Specificity | CD11a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CD11a protein. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment corresponding to a region within amino acids 723 and 947 of CD11a. |
Other Names | [CD11A; LFA-1; LFA1A; ITGAL; CD11 antigen-like family member A; integrin gene promoter; integrin alpha-L; leukocyte function-associated molecule 1 alpha chain; lymphocyte function-asso] |
Gene, Accession # | [CD11a], Gene ID: 3683, NCBI: NP_001107852.1, UniProt: P20701 |
Catalog # | MBS9401338 |
Price | $320 |
Order / More Info | CD11a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |