MAPK8 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | MAPK8 |
| Clone | polyclonal |
| Host Species | Chicken |
| Reactive Species | baboon, human, monkeypredicted: mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 0.5 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Overview: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. Phosphorylates the replication licensing factor CDT1, inhibiting the interaction between CDT1 and the histone H4 acet |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 370-420 on human Mitogen-activated protein kinase 8. Conjugation: Unconjugated |
| Other Names | [Affinity Purified Mitogen-activated protein kinase 8; AI849689; c Jun N terminal kinase 1; JNK 1; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; Mitogen-activated protein kinase 8; p54 gamma; Prkm8; Protein kinase JNK1; Protein kinase, mitogen-activated, 8; SAPK 1; SAPK gamma; Stress-activated protein kinase 1; Stress-activated protein kinase JNK1] |
| Gene, Accession # | [MAPK8], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
| Catalog # | MBS5400522 |
| Price | $390 |
| Order / More Info | MAPK8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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