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Antigenic Specificity | Ubiquitin-conjugating enzyme E2 K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Ubiquitin-conjugating enzyme E2 K polyclonal antibody. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein.Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquit |
Immunogen | Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 K protein |
Other Names | [Huntingtin-interacting protein 2; Ubiquitin carrier protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-protein ligase; UBE2K; HIP2; LIG] |
Gene, Accession # | Gene ID: 3093, NCBI: NP_001104582.1, UniProt: P61086 |
Catalog # | MBS9416124 |
Price | $320 |
Order / More Info | Ubiquitin-conjugating enzyme E2 K Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |