RIPK3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RIPK3 |
| Clone | [2013CT892.86.49] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RIPK3 antibody is generated from a mouse immunized with a recombinate protein from the human region of human RIPK3. Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
| Immunogen | n/a |
| Other Names | [Receptor-interacting serine/threonine-protein kinase 3; 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3; RIPK3; RIP3] |
| Gene, Accession # | [RIPK3], Gene ID: 11035, NCBI: Q9Y572.2, UniProt: Q9Y572 |
| Catalog # | MBS9231337 |
| Price | $165, $370 |
| Order / More Info | RIPK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yu P.W.,et al.Curr. Biol. 9:539-542(1999). Sun X.,et al.J. Biol. Chem. 274:16871-16875(1999). Yang Y.,et al.Biochem. Biophys. Res. Commun. 332:181-187(2005). Heilig R.,et al.Nature 421:601-607(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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