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Antigenic Specificity | MCM3AP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Isoform GANP: Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells (By similarity). Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclea |
Immunogen | Immunogen: Recombinant Human Germinal-center associated nuclear protein (292-435AA) |
Other Names | [Germinal-center associated nuclear protein; GANP; 80 kDa MCM3-associated protein; MCM3 acetylating protein (EC:2.3.1.-); MCM3AP; MCM3 acetyltransferase; MCM3AP; GANP; KIAA0572; MAP80] |
Gene, Accession # | [MCM3AP], Gene ID: 8888, NCBI: NP_003897.2, UniProt: O60318 |
Catalog # | MBS7104989 |
Price | $160, $235 |
Order / More Info | MCM3AP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |