Edit |   |
Antigenic Specificity | Phospho-SMAD4 (T277) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4. Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor. |
Immunogen | n/a |
Other Names | [Mothers against decapentaplegic homolog 4; MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4; SMAD4; DPC4; MADH4] |
Gene, Accession # | [SMAD4], Gene ID: 4089, NCBI: NP_005350.1, UniProt: Q13485 |
Catalog # | MBS9207554 |
Price | $165, $370 |
Order / More Info | Phospho-SMAD4 (T277) Antibody from MYBIOSOURCE INC. |
Product Specific References | Sekiya, T., et al., Biochem. Biophys. Res. Commun. 320(3):680-684 (2004). Horvath, L.G., et al., Prostate 59(3):234-242 (2004). Li, L., et al., Mol. Cell. Biol. 24(2):856-864 (2004). Wan, M., et al., J. Biol. Chem. 279(15):14484-14487 (2004). Maru, D., et al., Oncogene 23(3):859-864 (2004). |