Phospho-MAP2K2-T394 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-MAP2K2-T394
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chr
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding T394 of human MAP2K2 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[Phospho-MAP2K2-T394: CFC4; MEK2; MKK2; MAPKK2; PRKMK2], [MAP2K2; MAP2K2; CFC4; MEK2; MKK2; MAPKK2; PRKMK2; MEK2; MKK2; PRKMK2; MAP kinase kinase 2; MAPKK 2; MEK 2]
Gene, Accession #[MAP2K2], Gene ID: 5605, NCBI: P36507.1, UniProt: P36507
Catalog #MBS128294
Price$235, $350, $525
Order / More InfoPhospho-MAP2K2-T394 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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