CTLA4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CTLA4 |
| Clone | [AT4C8] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,k |
| Format | Protein A purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CTLA4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that downregulates the immune system. CTLA4 is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Mutations in CTLA4 have been associated with insulin-dependent diabetes mellitus, Graves' disease, Hashimoto's thyroiditis, celiac disease and other autoimmune diseases. |
| Immunogen | Immunogen: Recombinant human CTLA4 (36-161aa) purified from E. coli |
| Other Names | [Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor; Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor; CD; CD152; CELIAC3; GRD4; GSE; ICOS; IDDM12], [CSF1R; CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R; FMS; CSF-1-R; CSF-1R; M-CSF-R] |
| Gene, Accession # | [CTLA4], Gene ID: 1436, NCBI: NP_005202, UniProt: P07333 |
| Catalog # | MBS200264 |
| Price | $240, $315 |
| Order / More Info | CTLA4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dariavach. P., et al. (1988) Eur J Immunol 18 (12): 1901-1905; Waterhouse. P., et al. (1995) Science 270 (5238): 985-988; Magistrelli. G., et al. (1999) Eur J Immunol 29 (11): 3596-3602 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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